I would say the bubble in the seam is an issue. As well, the cordova top coming up is an indicative sign there are underlying issues under the top. If neither is addressed, the damage will of course escalate. I would bet money that if the cordova top was removed, it's ugly head would show under the trim and around the sail panel areas.

Better to negotiate a price $500-800 lower than asking if you want the car. The removal 9if required) and repair of that panel, if salvageable would run you $4-500. The removal of the filler is not typically necessary and can be done on car. Add another $100 for the top and unknown amount to repair/correct the damages under the top. The repairs will be more expensive if you choose to not replace the top as there may be a lot of work and filler material needed as well as labor.

I know...had to have my rear filler seams re soldered and repainted. My 67 is showing the same.