This is something I've seen dozens of times over the years (and I'm old!). Someone has a problem with a carb, they want to junk it and buy another brand. Then years later, THAT carb needs a rebuild, and then they want to change brands again, each time referring to the last carb as a POS. As for a Holley vs. Q-Jet debate, all you have to look at are the people that switched from Brand A to Brand B, then ask why. 9 out of 10 times it's because their existing carb needed a rebuild, and they didn't want the hassle, so they bought the other brand. And of course a brand new carb will wake up your vehicle, so they claim their old carb was a POS.
IMO, rebuild the Holley 650. There's nothing more gratifying than rebuilding something yourself, and it works. It's an art that's been lost in this disposable, throwaway society we live in today.
Holleys are performance carbs, Quadrajets are not. Quadrajet rebuilders will tell you different, but Holleys have powered every NASCAR car for the past 50 years, every NHRA Pro Stock car since Pro Stock was invented. When engine builders are building for horsepower, they don't use a Quadrajet, unless the engine is for a restoration, or is required for class rules.