I'm building a similar engine right now. 350 with TRW forged pistons, 62 (if I remember right)heads. One thing you need to watch is your exhaust vavle clearance. Exhaust valves will hit the cylinder wall with around .475 lift. I should get my block back next week and that is one of the things I need to measure before ordering a cam.
Holly does make 650 spread bore carb. I've got one running on my Mopar 340 and it works very well.
-=>Lee<=- Due to budget constraints the "light at the end of the tunnel" has been turned off!