There are a couple of great threads on timing going right now...I'm learning some new tricks too.

Set the timing first, with vacuum advance disconnected. Then double check the dwell, as it will change. Then verify timing again. Don't worry about the vacuum canister retard port, it's not going to affect a tuneup.

Once the timing is set, set the idle speed at the recommended setting. Get the engine warm, make sure it's kicked off the choke and fast idle. Set the curb idle speed, then adjust the mixture for maximum vacuum. Vacuum gauge should be on manifold vacuum, the small port in front of the carb is handy. Reset the curb idle and tweak the mixture as necessary. Be sure to start the mixture screws with equal settings (engine off), 2 1/2 turns out from lightly seated should be richer than necessary so you only need clockwise adjustments to tune it. Verify with the engine running by turning each mixture screw counterclockwise half a turn. If the engine does not speed up, return screws to their previous setting and start tuning. 1/4 turn in on each screw, listen to the engine. It should speed up slightly, and the vacuum reading should increase. Adjust the idle speed back to spec, note vacuum reading. Another 1/4 turn on each screw. Readjust idle, check vacuum. Continue until vacuum reading is at its highest point with the idle speed at book value.

You'll know when to stop when the engine runs a bit more roughly and vacuum readings start to decline. Back off to the previous setting, and I back off an additional 1/8 turn on each screw.

Side note: make sure both mixture screws are identical in length and profile. I was trying to tune one once that had a late model and an early mixture screw and there was no way that it was going to tune with equal treatment.