If you want to run high compression there are two things that help the most. First is to have the block 0-decked. and second use a cam with at least 112 deg and early intake valve opening.
I just don't get the mind set that people have a 400 car or put a 400 in a car and then de tune it so every small block chevy or Subaru goes blowing by. If you want less power get a 350 or 326. I just say don't let the good rep of high preformance Pontiac get laughed at .
My own car has 400 0-deck 68 #16 heads crower 60916 cam 1.65 rockers and I have put 5,000 miles on it running 93 octane with no sign of ping or detionation.
Alsow,I have demonstrated to the locals enough power that they don't try to beat me on the street.