Headers, Pypes full, out the back, dual 2.5" x pipe system w/50 series Delta Flow Flowmasters on my '68. Mildly loud but not obnoxious. Nice interior sound. I took off the Pypes Street Pros - nice sound at idle and when mashing the loud pedal but droned like mad at speed. Couldn't stand it. Pypes took a lot of work to get the up-and-over axle tubes to fit right. Like cutting & welding work. PITA for the money!
A friend of mine put a Pypes system on their '63 Nova. He was so pissed at the fit he finally took it off and threw it away after several weeks of fitting. He started with Violators... super loud with just a warmed over small block Chevy. Crappy sound to boot. He then switched to the Street Pros I took off of my car. Not too bad with a SBC but louder than the 50 series Flowmasters.
My 2 cents... Next time I'm going to try something other than Pypes. Maybe a Magnaflow system. I like the bigger case Flowmaster mufflers but you have to want to make them fit on our cars.