There are maybe three cars on this forum that are stock? As in every nut, every bolt, valve job, gasket untouched since Pontiac first assembled the car?
Anything else is fruit cocktail. Saying that this car likes 100 (what they were designed to run, RON rating which is approximately 95 or 96 (R+M)/2) or that another car likes 98, or that 400 likes 36 degrees total timing all in at 3500 rpm with a 3.55 or this 350 likes it all in at 2800 with a 2.76 isn't going to help the owner of a 326 2bbl or a RA IV very much, stock or not.
I don't have the background to do more than record what I have, make a best-guess change in a small increment, test, and either refine or reverse course until I get what I'm looking for. But this takes time, it takes good recordkeeping, and sometimes it takes inspiration from others to get past a roadblock.
If there's one thing I've learned, it's hard to improve on the original design without a plan and thorough knowledge of what each change will effect.
Vikki 1969 Goldenrod Yellow / black 400 convertible numbers matching